How we work Tap to expand Collapse
- Request Message us on Telegram, WhatsApp, or Viber with the medication name, dosage, and quantity.
- Confirmation The operator finds the medication at the best price and tells you the final cost, including delivery.
- Payment We accept payment in whichever way is convenient for you.
- Purchase We buy the original on your behalf from a licensed pharmacy in Germany.
- Shipping We pack it, photograph the contents and the parcel, and send it with a tracking number. For countries outside the EU, we prepare the customs paperwork.
- Delivery You receive your parcel. We stay in touch for any questions.
Amineurin (Amineurin)
Active substance: amitriptyline
Strengths: 10 mg, 25 mg, 50 mg, 100 mg
Shelf life: long
Indications: depression of various aetiologies (particularly with marked anxiety and agitation), including endogenous, involutional, reactive and neurotic depression, depression in organic brain damage, and drug-induced depression; schizophrenic psychoses, mixed emotional disorders, behavioural disorders, bulimia nervosa, childhood enuresis (except in children with bladder hypotonia), chronic pain syndrome (of neurogenic origin), prevention of migraine
Pack: 20, 50, 100 pcs
Instructions for use: Amineurin (Amineurin)
Brief reference information compiled from official German sources (Gelbe Liste, Fachinfo, Apotheken Umschau). It does not replace a doctor’s consultation or the package insert. This is a prescription medicine — use it only as directed by a doctor.
Active substance
Amitriptyline (as amitriptyline hydrochloride) — a tricyclic antidepressant. Manufacturer — Hexal AG, Germany.
Available forms
Film-coated tablets: 10 mg, 25 mg, 50 mg (Amineurin 10/25/50). Prolonged-release tablets 100 mg (Amineurin 100 retard).
Indications
- Depression in adults (episodes of major depression)
- Neuropathic pain in adults
- Prevention of chronic tension-type headache in adults
- Prevention of migraine in adults
How to take
The dose is selected by the doctor on an individual basis: treatment begins with a low dose and is increased gradually. In depression the usual starting dose is 25 mg twice a day; if necessary, the doctor gradually increases it up to a maximum of 150 mg/day (in two divided doses). In neuropathic pain and the prevention of migraine/tension-type headache the doses are lower: a starting dose of 10–25 mg in the evening, with a usual daily dose of 25–75 mg. In elderly patients (over 65 years) and patients with cardiovascular disease, treatment begins with 10–25 mg; in the elderly the daily dose is usually no higher than 100 mg. The tablets are swallowed whole with water. The antidepressant effect does not occur immediately — usually after 2–4 weeks; with pain, improvement may also take several weeks. Treatment of depression usually continues for at least 6 months. The medicine must not be stopped abruptly — the dose is reduced gradually under the doctor’s supervision (abrupt withdrawal may cause headache, malaise, insomnia and irritability).
Contraindications
- Allergy to amitriptyline or the medicine’s components
- Recent myocardial infarction
- Cardiac rhythm disturbances (on ECG), heart block, coronary heart disease
- Concurrent use of MAO inhibitors, or fewer than 14 days after their discontinuation
- Severe liver disease
- Acute poisoning with alcohol, hypnotics or analgesics; untreated angle-closure glaucoma, urinary retention (based on the active substance’s profile)
- Children under 6 years; it is not prescribed to children and adolescents for the treatment of depression
Possible side effects
- Dry mouth
- Drowsiness, sluggishness
- Constipation
- Dizziness, including on standing up due to a drop in blood pressure (orthostatic hypotension)
- Weight gain
- Rapid heartbeat, sweating
- Trembling of the hands (tremor), blurred vision (impaired accommodation)
Special precautions
Prescription medicine (verschreibungspflichtig). Pronounced anticholinergic effects: in the elderly there is an increased risk of confusion and delirium, so treatment in them is started at minimal doses (10–25 mg in the evening). Cardiac risks: QT-interval prolongation and arrhythmias are possible; in heart disease and at doses above 75–100 mg/day more frequent monitoring (ECG) is required. It causes drowsiness and dizziness, especially at the start of treatment — you must not drive or operate machinery until your individual response is clear. Alcohol enhances the depressant effect — do not combine them. At the start of treatment for depression, suicidal thoughts may increase — a doctor’s supervision is required.
Sources: www.gelbe-liste.de, www.gelbe-liste.de, www.gelbe-liste.de, www.gelbe-liste.de, www.gelbe-liste.de, www.apotheken-umschau.de, www.apotheken-umschau.de
