Helmex

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Helmex

Strengths: 250 mg; 250 mg/5 ml
Active substance: pyrantel
Shelf life: long
Pack sizes: 4 tab.; suspension in 10 ml and 50 ml bottles
Indications: ascariasis; enterobiasis; hookworm infection, including necatoriasis

 

Instructions for use: Helmex

Brief reference information compiled from official German sources (Gelbe Liste, Fachinfo, Apotheken Umschau). It does not replace a doctor’s consultation or the package insert. This is a prescription medicine — use it only as directed by a doctor.

Active substance

Pyrantel (as pyrantel embonate/pamoate). In the tablet, 250 mg of pyrantel corresponds to 720 mg of pyrantel embonate. Manufacturer — InfectoPharm. ATC code P02CC01.

Available forms

  • 250 mg chewable tablets (Helmex Kautabletten) — contain 720 mg of pyrantel embonate = 250 mg of pyrantel; can be divided into two equal doses; approved from 2 years of age
  • Oral suspension 250 mg/5 ml (Helmex Suspension) — suitable for children from 6 months of age

Indications

Treatment of intestinal helminthiases (nematode infections) caused by: pinworms (Enterobius vermicularis), roundworms (Ascaris lumbricoides), hookworms (Ancylostoma duodenale), the American hookworm/necator (Necator americanus), as well as Trichostrongylus colubriformis and orientalis.

How to take

The standard dose is 10 mg of pyrantel per kg of body weight as a single dose (maximum single dose 1 g). In enterobiasis (pinworms) the dose is repeated after 2–4 weeks. In uncomplicated ascariasis the dose may be halved. In severe Necator americanus infestation — 20 mg/kg on two consecutive days, or the standard dose on three consecutive days. It is taken regardless of meals or time of day, and laxatives are not required. After treatment, a follow-up stool test is advisable if recommended by the doctor. The specific dose and regimen are determined by the doctor.

Contraindications

  • Hypersensitivity to pyrantel
  • Existing liver disease
  • Children under 6 months of age (pyrantel is not used)
  • Tablets — in children under 2 years of age
  • Pregnancy — only where there are strict medical indications (safety data are insufficient)

Possible side effects

  • Headache
  • Dizziness
  • Intestinal cramps (abdominal pain)
  • Nausea
  • Vomiting
  • Diarrhoea
  • Elevated liver transaminases

Special precautions

In Germany the medicine is prescription-only (rezeptpflichtig/verschreibungspflichtig) — dispensed on prescription. In pinworm infection, close contacts may be infected without symptoms, so it is advisable to treat all family members. Hygiene measures are important: thorough washing of bed linen and clothing, and cleaning of living quarters. After treatment, a follow-up stool test is advisable if recommended by the doctor. It must not be combined with piperazine (mutual antagonism). With theophylline, its blood level may rise, so monitoring is needed.

Sources: www.gelbe-liste.de, www.gelbe-liste.de, www.gelbe-liste.de, www.apotheken-umschau.de, www.apotheken-umschau.de